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Interaction between Two Unlinked Disease Loci under Six Two-Locus Disease Models
| Second Locus |
||||
| Model and First Locus |
D2D2 | D2d2 | d2d2 | Interaction Measure |
| Dom ∪ Dom: | -Pd1Pd2f2 | |||
| D1D1 | f | f | f | |
| D1d1 | f | f | f | |
| d1d1 | f | f | 0 | |
| Rec ∪ Rec: | -PD1PD2f2 | |||
| D1D1 | f | f | f | |
| D1d1 | f | 0 | 0 | |
| d1d1 | f | 0 | 0 | |
| Threshold: | -P2D1P2D2f2 | |||
| D1D1 | f | f | 0 | |
| D1d1 | f | 0 | 0 | |
| d1d1 | 0 | 0 | 0 | |
| Dom ∪ Rec: | -Pd1PD2f2 | |||
| D1D1 | f | f | f | |
| D1d1 | f | f | f | |
| d1d1 | f | 0 | 0 | |
| Epistasis: | -PD1P2D2f2 | |||
| D1D1 | f | f | 0 | |
| D1d1 | f | 0 | 0 | |
| d1d1 | f | 0 | 0 | |
| Modifying: | -P2D1PD2f2 | |||
| D1D1 | f | f | f | |
| D1d1 | f | 0 | 0 | |
| d1d1 | 0 | 0 | 0 | |
