Table 2. .

Synthesis of Individual Mitochondrial Polypeptides in Fibroblasts from Patients P1 and P2 after Pulse Labeling with [³⁵S]Methionine^[Note]

	Incorporation of [35S]Methionine(% of Control)
Polypeptide	P1	P2	P1 + EFTu	P1 + EFTs
ND5	22	18	59	49
COI	34	32	59	61
ND4	42	33	65	52
ND2/cytb	61	51	56	43
ND1	56	55	58	46
COIII/COII	42	34	56	60
ATP6	134	64	69	31
ND6	59	21	60	72
ND3	103	68	112	91
ND4L	29	30	43	48
ATP8	244	113	94	22

Note.— The results are presented as a percentage of the average incorporation of [³⁵S]methionine in two relevant controls. Mitochondrial translation was also analyzed in patient 1 after transduction with retroviral constructs overexpressing EFTu or EFTs. COI–COIII = subunits of cytochrome c oxidase; cytb = cytochrome b subunit; ND1, ND2, ND3, ND4, ND4L, ND5, and ND6 = subunits of NADH CoQ oxidoreductase.