Table 1. Reported fatty acyl-CoA preferences of mammalian LASS family members.
LASS genes having the same number are very closely related. Shown are human and mouse homologues, the human ones in capitals.
| Current name | Old name | Accession number | Mammalian cells in vivo | Mammalion cells in vitro | Yeast in vitro |
|---|---|---|---|---|---|
| LASS1 | UOG1 | NM_021267 | – | – | C26:0 [25] |
| Lass1 | uog1 | NM_138647 | C18:0 [55] | C18:0 [27,55] | – |
| LASS2 | clone 1 | BC010032 | – | – | C24:0 [25] |
| Lass2 | trh3 | BC006847 | VLCFA> | C22:0>C24:0>C26:0 ≈ | – |
| LCFA [27] | C18:0 [27] | ||||
| Lass3 | XM_907730 | C24>C22:0≈C18:0 | C18:0≈C22:0≈C24> | – | |
| C26:0≈C16:0>C20:0 [54] | |||||
| LASS4 | clone 4 | AK022151 | – | – | C24:0>C20:0>C18:0 [25] |
| Lass4 | trh1 | BC003946 | C18:0> | C22:0>C24:0≈C18:0> | – |
| C20:0> | C26:0>C16:0>C14:0 [27] | ||||
| C22:0 [26] | and C18:0>C20:0>C22:0 [26] | ||||
| Lass5 | trh4 | BC046797 | C16:0 only [26] | C14:0≈C16:0≥C18:0≈ | C12:0≈14:0≈ |
| C18:1>C12:0 [27] | C16:0≈C18:0≈C18:1 this study | ||||
| Lass6 | trh1 like | BC057629 | LCFA>VLCFA [27] | C14:0≈C16:0≥C18:0≈C12:0 [27] | – |