Table 3. .

Fasting Glucose Results for rs1799884 and rs3757840 for All Cohorts in the Present Study^[Note]

	Mean (SD) Glucose Level [No. of Subjects] for
	rs1799884				rs3757840
Study	GG	GA	AA	Dominant P	CC	CA	AA	Linear Trend P
ALSPAC Children	4.90 (.32) [506]	4.98 (.32) [207]	4.95 (.35) [21]	.008	4.87 (.32) [174]	4.94 (.32) [368]	4.95 (.32) [180]	.02
BCG	4.57 (.38) [426]	4.64 (.37) [180]	4.48 (.45) [18]	.13	4.57 (.41) [127]	4.59 (.36) [324]	4.64 (.40) [166]	.10
EFS	4.50 (.43) [988]	4.58 (.44) [449]	4.53 (.51) [55]	.01	4.48 (.42) [350]	4.53 (.43) [714]	4.57 (.48) [407]	.02
PEB	4.65 (.69) [224]	4.75 (.41) [94]	4.66 (.48) [14]	.08	4.61 (.44) [81]	4.69 (.45) [172]	4.79 (.48) [76]	.01
BWHHS	5.49 (.39) [1,671]	5.54 (.37) [678]	5.60 (.28) [69]	.001	5.48 (.41) [594]	5.51 (.38) [1,238]	5.53 (.35) [578]	.03
InChianti	4.77 (.49) [657]	4.82 (.51) [321]	4.95 (.47) [44]	.03	4.76 (.51) [178]	4.79 (.49) [456]	4.80 (.50) [293]	.40

Note.— Glucose is measured in mmol/liter. The data are presented in ascending order of the median age of the cohort. We chose to present the data this way because of the relatively few AA genotypes for rs1799884 and because our previous data¹⁵ and the initial cohort suggested a dominant model. However, given the high frequency of the rs3757840 minor allele and the data from the EFS, an additive model appeared to fit best for this SNP.