Figure 2. .

Structure of human RPS24 gene. a, Schema of the two variants of human RPS24, ^NCBI accession numbers NM_033022 (variant 1) and NM_001026 (variant 2), as a result of alternative 3′-end mRNA splicing.¹⁴ Variant 1 contains exons I–V and encodes RPS24 isoform a (130 aa) (NP_148982). Exon V encodes the stop codon (tga). Variant 2 contains exons I–IV and VI and encodes RPS24 isoform c (133 aa) (NP_001017). Exon VI encodes 3 aa, PKE. b, Schema of the novel human RPS24 variant 3, which contains exons I–IV and VII and encodes the 131-aa RPS24 isoform (isoform b). Below it is the sequence of the novel human RPS24 transcript variant 3. The ATG in bold uppercase letters represents the start codon. Alternatively spliced 3′ end of transcript variant 3 encodes Lys (AAA [red uppercase letters]) followed by stop codon tga. Red lowercase letters represent the untranslated region of exon VII, green letters represent untranslated exon V, and blue letters represent untranslated exon VI of the novel RPS24 transcript variant 3.