Table 1.

Evaluation of Colonization and Histopathology in the Four Treatment Groups

Group	Treatment	Colonization* (antrum)†	Lymphoid aggregates‡	Lymphoepithelial lesions‡	MALT lymphoma§
A	Nil	0	0	0	0/6
B	Hf alone	3.6	2.2	2.1	3/12
C1¶	Hf + TT	0	0.67	0.3	0/6
C2∥	Hf + TT	2.5	3.0	2.25	1/2
D	Hf + TT + Hf	3.3	2.3	2.1	4/9

^*Paraffin sections were stained with May-Grünwald-Giemsa for grading of bacterial colonization on a 0 to 4-point scale in four different regions of the stomach (antrum, body, antrum/body, and body/cardia transitional zones). 

^†Colonization levels in the antrum are shown because they are representative of overall colonization. 

^‡Hematoxylin and eosin-stained sections were also evaluated for histopathological changes: the presence of lymphoid aggregates and lymphoepithelial lesions were graded on a 0 to 3 scale. All slides were coded and examined blind. 

^§A diagnosis of low-grade lymphoma was made independently (M.F.D.). 

^¶Six of eight animals in group C were successfully treated. 

^∥The treatment of two of eight animals in group C was not successful. 

Hf, Helicobacter felis; TT, triple therapy.