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. 2005 Sep;167(3):651–661. doi: 10.1016/s0002-9440(10)62040-8

Figure 1.

Figure 1

NHBE cells were exposed to HNE throughout a range of times and concentrations. A: NHBE cells were exposed to 1 μmol/L HNE or vehicle control for 5, 10, 20, 30, or 60 minutes, and mucin secretion was quantified by ELISA as described in the text using the 17Q2 antibody. Mucin secretion was rapidly increased after exposure to HNE and appeared to plateau at 10 to 15 minutes. B: HNE stimulates mucin secretion from NHBE cells in a concentration-dependent manner after 15 minutes of exposure. Cells were exposed to HNE for 15 minutes and mucin secretion was quantified by ELISA as described in text using 17Q2 antibody. *, Significantly different from vehicle control (P < 0.005). †, Significantly different from vehicle control (P < 0.001). Data are presented as mean ± SEM (n = 6 at each point in A, 12 at each point in B).