Figure 4.

Delayed hair follicle morphogenesis in K14-dnActRIB transgenic mice. A: Pelage hair follicles in the back skin of K14-dnActRIB transgenic and wild-type mice 1 day after birth were evaluated according to the hair follicle morphogenesis stages defined in Paus and colleagues.25 Higher values indicate later stages in the hair cycle, *P = 0.018. B: Pelage hair follicles were categorized at the end of the first hair cycle at day 17 pp. C: The percentage of Ki67-positive cells underneath the Auber’s line in pelage hair follicles was determined at day 17 pp. Error bars indicate standard errors of mean. The significance of the difference between wild-type and transgenic mice was determined by Student’s t-test. *P < 0.05, **P < 0.01; P values determined with analysis of variance test.