Figure 7.
Effect of FT deficiency on eotaxin-induced eosinophil accumulation in skin. Eotaxin (10 pmol/kg) was injected intradermally to dorsal skin and EPO activity in skin was measured 4 hours later. Activities of EPO in FT-IV- and FT-VII-deficient mice were similarly reduced. Eosinophil recruitment was virtually absent in doubly-deficient mice. Results are from a single representative of three separate experiments. Each group consisted of at least four mice. Error bars indicate SD. *P < 0.05.