Figure 4.

Decreased acquisition of spontaneous metastatic ability of B16BL6 melanoma cells after subcutaneous injection into gp91^phox−/− mice. B16BL6 melanoma cells (1 × 10⁶) were injected subcutaneously into WT mice and gp91^phox−/− mice. The mice were sacrificed for necropsy when they were in a moribund state. *P < 0.05 and **P < 0.01 versus WT mice.