Figure 4.

Cell fates of newly generated cells 1 day after BrdU labeling reveal that excess TGF-β1 does not alter the proportion of cells becoming neurons versus astrocytes. Microglia were excluded from this analysis because they are not derived from neural progenitor cells. Note the area of each pie graph represents the absolute number of new cells; TGF-β1 mice generate only 40% of the normal number of new cells, but the proportion of cells assuming each phenotype in TGF-β1 mice is not altered compared to wild-type mice.