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Dual immunofluorescence analysis of renal cortex from 7-week-old Alport and wild-type mice. Cryosections from wild-type and Alport mouse kidneys were immunostained with antibodies specific for MMP-12 (A and D) and CD11b (B and E). Dual immunostaining (C and F) illustrates that monocytes (red) are immunonegative for MMP-12 (green) while glomeruli are immunopositive for MMP-12.
