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. 2006 Jul;169(1):86–95. doi: 10.2353/ajpath.2006.050612

Figure 7.

Figure 7

IGF mediates fibroblast prosurvival signal in ARDS BALF. Fibroblast apoptosis was measured 48 hours following incubation of normal human lung fibroblast with BALF with or without IGF neutralizing antibody (5 ng/ml) from at-risk patients (A) or ARDS patients (B). Apoptosis was measured by Cell Death ELISA-plus ELISA (Roche Applied Science) per the manufacturer’s directions. All experiments were done in triplicate and repeated at least twice. Data are reported as the mean OD415 nm ± SD. *Significant difference (P< 0.05) from BALF alone.