Figure 1-6929.

Integrin α_vβ₈ is expressed by fetal tracheal epithelial cells and fibroblasts. Immunohistochemistry of fetal tracheas was performed using integrin β₈ (A–C) and β₆ (D) subunit-specific or phosphorylated SMAD-2 antibodies (E). In A, inset indicates area magnified in B. In C, the primary anti-β₈ antibody was preincubated with a GST-β₈ cytoplasmic domain fusion protein. Epithelial and mesenchymal staining is indicated by arrows and arrowheads, respectively. Scale bars: 50 μm (A, C–E); 10 μm (B).