Table 1.

Body, Kidney, and Uterus Weight, and Serum Estrogen Levels

Treatment	N	Body weight (g)	Kidney weight (g)	Kidney weight/ body weight (×103)	E2 (pg/ml)	Uterine weight (mg wet weight)
Sham	5	24.7 ± 0.1	0.13 ± 0.01	4.3 ± 0.2	12.32 ± 4.0	0.25 ± 0.03†
Placebo	6	25.88 ± 1.9	0.13 ± 0.03	5.2 ± 0.8	5.35 ± 1.6	0.09 ± 0.02
CE2	6	24.3 ± 2.2	0.16 ± 0.02*	6.5 ± 0.5*	20.39 ± 6.8*	0.15 ± 0.05*
IE2	5	24.8 ± 2.6	0.14 ± 0.02	5.6 ± 0.8	29.82 ± 7.9†	0.17 ± 0.02*
Tam	5	24.32 ± 1.3	0.11 ± 0.01	4.5 ± 0.3	ND	0.04 ± 0.02

CE₂, continuous 17β-estradiol treatment; IE₂, intermittent 17β-estradiol treatment; Tam, tamoxifen; ND, not done.

^*P < 0.05,

^†P < 0.005 compared to placebo.