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. 2006 Aug;169(2):372–387. doi: 10.2353/ajpath.2006.060043

Figure 4-6944.

Figure 4-6944

α-SMA is induced during ischemia-reperfusion injury of the kidney in a CX3CR1-dependent manner. A: Histopathological analysis of outer medulla. i: CX3CR1-deficient mice stained with anti-α-SMA; ii and iii: wild-type mice stained with anti-α-SMA and control IgG, respectively. B: Quantitation of histopathological data. −/−, CX3CR1 knockout mice; +/+, wild-type control mice; sham, sham-operated wild-type mice tested 24 hours after surgery. Values are mean ± SEM and represent data from three independent experiments with four to five animals in each experiment. *P < 0.05, comparing CX3CR1-deficient mice versus wild-type mice. Original magnifications, ×320.