Figure 5-6944.

CX3CR1 specifically regulates macrophage infiltration of the outer medulla after renal ischemia-reperfusion injury. −/−, CX3CR1 knockout mice; +/+, wild-type control mice; sham, sham-operated wild-type mice tested 24 hours after surgery. A–C: Quantitation of density of indicated leukocyte subsets in tissue sections under the conditions shown. Values are mean ± SEM and are from three independent experiments with four to five animals in each experiment. *P < 0.05 comparing CX3CR1-deficient mice versus wild-type mice at the same time point. Original magnifications, ×320.