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. 2006 Aug;169(2):433–444. doi: 10.2353/ajpath.2006.051330

Figure 9-6932.

Figure 9-6932

B. anthracis versus E. coli challenge in the baboon. Plasma levels of IL-8 (A, B), MCP-1 (C, D), MIP-1 (E, F), IL-12p70 (G, H), and IL-12p40 (I, J) were determined by assays from baboons challenged with B. anthracis (top) or E. coli (bottom). Challenge B. anthracis dose in CFU/kg: 105 to 106 (▿, n = 2); 107 (□, n = 3); 108 (•, n = 3); and 109 (▴, n = 3). Challenge E. coli dose in CFU/kg: 108 (▿, n = 3); 109 (□, n = 2); 1010 (•, n = 3). Mean ± SEM. A–H: There were significant differences between lethal challenges with 108 CFU/kg B. anthracis and 1010 CFU/kg E. coli; *P < 0.05, ***P < 0.001. I and J: There were significant differences between sublethal challenge with 105 to 106 CFU/kg B. anthracis and 108 CFU/kg E. coli; **P < 0.01.