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. 2006 Sep;169(3):943–953. doi: 10.2353/ajpath.2006.051319

Figure 3.

Figure 3

Morphologically normal L. donovani granulomas develop in the liver parenchyma but not in the egg granulomatous areas of S/L mice. H&E-stained sections of liver show comparable mature L. donovani granulomas in the parenchyma of L (A) and S/L (B) mice. C and D: Dispersed amastigote-laden macrophages (arrows) within the egg granulomas of S/L mice do not elicit discrete cellular foci. EG, S. mansoni egg. E: Heavy accumulation of amastigotes (arrows) within giant cells occupying a schistosome egg shell at the center of an egg granuloma. All sections are from mice at +8 weeks after superinfection. Original magnifications: ×400 (A, B); ×1000 (C, E); ×1600 (D).