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Time course of neutrophil (A), lymphocyte (B), and macrophage (C) influx into the BAL from mutant and wild-type mice. BAL was collected at 2, 4, 8, 12, and 16 days after intratracheal bleomycin administration. Saline-treated mutant mice or wild-type mice showed no significant increase in leukocyte numbers (data not shown). All values represent the mean ± SEM of results obtained using eight mice in each group. Statistical analysis is presented in the Results section.
