Figure 7.

Lack of NK1.1⁺ cells augmented bleomycin-induced lung fibrosis. The mean pathological score (A), lung hydroxyproline content (B), and total leukocyte counts from BAL fluid (C) of wild-type mice, wild-type mice injected with anti NK1.1 mAb, E-selectin^−/− mice injected with anti-P-selectin mAb, and E-selectin^−/− mice injected with anti-P-selectin mAb and anti-NK1.1 mAb. Lungs were harvest 16 days after bleomycin administration. The pathological scores, hydroxyproline assay, and BAL cell counts were as described in the Materials and Methods section. The results were obtained from four mice in each group.