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. 2006 Oct;169(4):1238–1250. doi: 10.2353/ajpath.2006.051136

FIGURE 3.

FIGURE 3

Effects of in vivo administration of gefitinib on the liver and kidney cyst pathology of the PCK rat. Control and PCK rats were treated with gefitinib or vehicle alone daily between 3 and 10 weeks of age. AE: Representative liver sections stained with azan-Mallory. FJ: Representative kidney sections stained with H&E at the same magnification. Gefitinib improved cystic dilation of intrahepatic bile ducts of PCK rats, but no beneficial effects were observed on kidney lesions. Original magnifications, ×20 (AE).