Skip to main content
. 2006 Oct;169(4):1312–1327. doi: 10.2353/ajpath.2006.051333

FIGURE 7.

FIGURE 7

Increased number of inflammatory cells and MMP activity in Hoxa5−/− BALF. A: Differential cell counts showed an increase of macrophages, lymphocytes, and neutrophils in Hoxa5−/− specimens when compared with controls. Statistically significant differences are denoted by asterisks (**P < 0.002, ***P < 0.0001). Diff-Quik staining also revealed that Hoxa5−/− BALF contained large, vacuolated macrophages with dark inclusions not seen in control samples (B, C). D: MMP activities in wild-type (+/+) and Hoxa5−/− (−/−) alveolar macrophage-conditioned media in gelatin gel zymogram. Data are presented as the reverse image of the original zymogram. Conditioned media from the HT1080 cell line served as a positive control (ctl). Slightly elevated MMP2 and MMP9 activities were observed in Hoxa5−/− alveolar macrophage-conditioned medium. Scale bar = 50 μm.