. 2003 Aug 1;31(15):4461–4471. doi: 10.1093/nar/gkg632

Table 2. The synthesis yield of oligoribonucleotides containing 2-methylthio-N⁶-alkyladenosines via post-synthetic modification of precursor form of oligonucleotides.

	UACXUGUA		UXCAUGUA		UACAUGUX		ACAUGUX
	Yield^a	MS^b	Yield^a	MS^b	Yield^a	MS^b	Yield^a	MS^b
X = ms²A	48%	2541.02	49%	2540.91	27%	2541.01	35%	2234.65
X = ms²m⁶A	64%	2555.04	35%	2554.79	54%	2555.00	53%	2249.03
X = ms²i⁶A	41%	2608.93	24%	2608.97	65%	2608.57	20%	2302.92
CCGGUCmUCCAXAACCGG
	X = ms²A		X = ms²m⁶A		X = ms²i⁶A^c
	16%	5445.18	24%	5459.53	22%	5513.76

^aBased on C-18 HPLC analysis.

^bMeasured molecular weight of the oligoribonucleotides.

^cObtained from modified phosphoramidite.

Table 2. The synthesis yield of oligoribonucleotides containing 2-methylthio-N6-alkyladenosines via post-synthetic modification of precursor form of oligonucleotides.