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(A) RNA duplex sequences and the structures of N6-alkyladenosines and 2-methylthio-N6-alkyladenosines. (B) The structure of the anticodon loop of tRNATrp from E.coli, with modified nucleotides placed at position 37 of this sequence (the modified position is indicated by A*, and Cm is the naturally occurring 2′-O-methylcytidine).
