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. 2003 Aug 1;31(15):4326–4331. doi: 10.1093/nar/gkg654

Figure 5.

Figure 5

NMR solution structure of the HIV-1 frameshift inducing stem–loop. (A) Superimposition over all heavy atoms of the 20 conformers with the lowest energies calculated with the incorporation of RDCs. The r.m.s.d. over all heavy atoms for these 20 structures is 1.24 Å. (B) Stereo view of the lowest energy structure of the HIV-1 frameshift inducing stem–loop. View is into the minor groove of the stem and the major groove of the tetraloop. (C) Stereo view of the tetraloop and adjacent Watson–Crick pair from the 20 lowest energy conformers superimposed over nucleotides 9–14 (r.m.s.d. 0.47 Å). View is into the minor groove of the tetraloop and the molecule is rotated 180° relative to (B).