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. 1968 Nov;34(3):623–629. doi: 10.1111/j.1476-5381.1968.tb08491.x

Effect of rabbit antibodies against angiotensin-II on the pressor response to angiotensin-II and renal hypertension in the rat

P R Hedwall
PMCID: PMC1703526  PMID: 4302379

Abstract

1. In the intact or nephrectomized rat, the pressor responses to synthetic angiotensin-II-amide, beta-angiotensin-II and native “rat angiotensin” could be inhibited by intravenous injection of rabbit serum containing antibodies against synthetic angiotensin-II-amide.

2. The pressor responses to vasopressin or noradrenaline were not influenced by anti-angiotensin serum.

3. A single injection of anti-angiotensin serum inhibited the pressor responses to angiotensin-II-amide for a period of 2.5 hr.

4. Intravenous infusion or daily intraperitoneal injection of anti-angiotensin serum did not influence blood pressure levels in renal hypertensive rats.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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