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. 1963 Apr;20(2):221–229. doi: 10.1111/j.1476-5381.1963.tb01461.x

Action of sympathomimetic drugs on the isolated junction of the bile duct and duodenum

A Crema, F Berté
PMCID: PMC1703626  PMID: 14023764

Abstract

The actions of adrenaline, noradrenaline and phenylephrine were studied both on the terminal tract of bile duct (prepared as spiral strips or intact) and on the adjacent duodenum taken from the calf and the cat. These amines contract the terminal bile duct and relax the duodenum. Furthermore, on the basis of the action of some adrenaline antagonists, the hypothesis is advanced that there are α-receptors which mediate contraction of muscle in the sphincterial zone of the bile duct.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CREMA A., BENZI G., BERTE F. The action of some natural substances on the terminal portion of the common bile duct isolated "in toto". Arch Int Pharmacodyn Ther. 1962 Jun 1;137:307–317. [PubMed] [Google Scholar]
  2. CREMA A., BENZI G. [Behavior in vitro of Oddi's sphincter of animals]. Arch Fisiol. 1961 Sep 25;60:374–386. [PubMed] [Google Scholar]
  3. DE LA MATA R. C., PENNA M., AVIADO D. M. Reversal of sympathomimetic bronchodilation by dichloroisoproterenol. J Pharmacol Exp Ther. 1962 Feb;135:197–203. [PubMed] [Google Scholar]
  4. ERDMANN W. D., HENNE H. F. Uber spasmolytische Wirkungen am Sphincter Oddi. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1953;218(6):462–478. [PubMed] [Google Scholar]
  5. FOGLIATI A. E., CIOCATTO E., CATTANEO A. D., GIUDICE P. A. Les modifications du tonus des voies biliaires sous l'action de certains médicaments; recherches expérimentales de mamométrie biliaire. Arch Mal Appar Dig Mal Nutr. 1954 Apr;43(4):428–444. [PubMed] [Google Scholar]
  6. GRANSER G., HERTTING G., RISSEL E., WEWALKA F. Untersuchungen über die Beeinflussbarkeit des Sphinkter Oddi. Arch Int Pharmacodyn Ther. 1956 Mar 1;105(3-4):389–402. [PubMed] [Google Scholar]
  7. HERMANSEN K. The effect of adrenaline, noradrenaline and isoprenaline on the guinea-pig uterus. Br J Pharmacol Chemother. 1961 Feb;16:116–128. doi: 10.1111/j.1476-5381.1961.tb00304.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. LEVY B., AHLQUIST R. P. An analysis of adrenergic blocking activity. J Pharmacol Exp Ther. 1961 Aug;133:202–210. [PubMed] [Google Scholar]
  9. LUDUENA F. P. Smooth muscle contracting effects of levo-N-isopropl arterenol and adrenolytic action of its dextroisomer. Arch Int Pharmacodyn Ther. 1962 May 1;137:155–165. [PubMed] [Google Scholar]
  10. MENGUY R. B., HALLENBECK G. A., BOLLMAN J. L., GRINDLAY J. H. Intraductal pressures and sphincteric resistance in canine pancreatic and biliary ducts after various stimuli. Surg Gynecol Obstet. 1958 Mar;106(3):306–320. [PubMed] [Google Scholar]
  11. MUNRO A. F. The effect of adrenaline on the guinea-pig intestine. J Physiol. 1951 Jan;112(1-2):84–94. doi: 10.1113/jphysiol.1951.sp004510. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. POILLEUX F., GOIDIN, NICHOLAIDIS Dystonies biliaires fonctionnelles. Role du pneumogastrique droit; étude expérimentale et déductions chirurgicales. Presse Med. 1952 Feb 13;60(10):196–200. [PubMed] [Google Scholar]
  13. THOMPSON J. W. Studies on the responses of the isolated nictitating membrane of the cat. J Physiol. 1958 Apr 3;141(1):46–72. doi: 10.1113/jphysiol.1958.sp005954. [DOI] [PMC free article] [PubMed] [Google Scholar]

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