The increased cardiovascular risk in psoriasis may result from

• The increased prevalence of associated risk factors, such as smoking, obesity, hypertension and alcohol misuse.

• The use of dyslipidaemic therapies, such as corticosteroids, acitretin and ciclosporin.

• An associated unfavourable lipid profile (high triglycerides, low HDL).

• Endothelial dysfunction.

• Uncontrolled inflammation.

• Combination of some or all of the above.