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. 2003 Jul 18;100(16):9214–9219. doi: 10.1073/pnas.1533326100

Table 4. Single crystal structures for RNA·DNA hybrid duplexes.

Sequence Structure Space group Crystal packing Ref.
r(CAAAGAAAAG)·d(CTTTTCTTTG) Intercalation 1222 Abutting and head-to-head This work
RNA-C2′ endo for 2A, C3′ endo for others (1 and 1* and 20 and 20*)
DNA-C3′ endo
r(CAAAGAAAAG)·d(CTTTTCTTTG) A-like P212121 Abutting 25 and M.L.K., L. Lavelle, G.W.H., H.-L. Ng, and R.E.D., unpublished data
r(GAAGAAGAG)·d(CTCTTCTTC) A-like P61 Abutting 49
r(GAAGAGAGAG)·d(CTCCTCTTC) A-like flipped-out base 1222 Abutting and head-to-head, looped-out, bulge interaction 31
r(GAAGAGAAGC)·d(GCTTCTCTTC) A-like P212121 Abutting 50
r(GAAGAAGAA)·d(TTCTTBr5CTTC) A-like P61 Abutting 51
r(UUCGGGCGCC)·d(GGCGCCCGAA) RNA-C3′ endo P4322 Abutting and head-to-tail 52
DNA-C2′ endo for AA, C3′ endo for others (1 and 20*, and 20 and 1*)