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. 2003 Jul 23;100(16):9232–9237. doi: 10.1073/pnas.1533294100

Table 3. Analysis of the total protein list with respect to functional categories.

Proteins detected
Membrane proteins detected*
mRNA detected
Category Genes/proteins Membrane proteins* Mean no. of tryptic peptides predicted Mean mRNA signal (arithmetic) Mean mRNA signal (geometric) No. % No. % No. %
1 Cell processes 608 355 12.6 2,000 550 171 28.1 63 17.7 431 70.9
2 Extrachromosomal 92 12 14.2 1,270 210 8 8.8 4 33.3 25 48.1
3 Global functions 55 12 15.8 2,610 1,050 22 40.7 3 25.0 47 85.5
4 Macromolecule metabolism 315 43 19.4 3,100 1,090 156 49.7 15 34.9 283 89.8
5 Metabolism of small molecules 881 111 15.6 2,630 820 385 43.7 25 22.5 673 76.4
6 Miscellaneous 742 180 14.1 780§ 280§ 117 15.8 14 7.8 421 57.4§
7 Open reading frames 1,409 258 9.8 780 280 199 14.1 18 7.0 803 57.7
8 Structural elements 215 46 11.6 17,000 2,160 89 46.8** 18 39.1 1,369 78.6
9 tRNA 86 7,800 2,150 71 82.6
10 Sum or average†† 4,403 1,017 13.1 2,470‡‡ 490‡‡ 1,147 26.7** 160 15.7 2,923 67.4‡‡
*

High estimate.

Data are for all proteins/genes in category. The values for arithmetic means for expressed genes in each category were as follows: 1, 2,770; 2, 2,530; 3, 3,020; 4, 3,420; 5, 3,400; 6, 1,260; 7, 1,260; 8, 21,590; 9, 9,430; 10, 3,600. The values for geometric means for expressed genes were as follows: 1, 1,060; 2, 830; 3, 1,530; 4, 1,360; 5, 1,470; 6, 620; 7, 680; 8, 5,000; 9, 4,810; 10, 1,090.

Forty genes were not represented on Affymetrix GeneChips.

§

Nine genes were not represented on Affymetrix GeneChips.

This is the same as proteins of unknown function in Tables 1 and 2.

Seventeen genes were not represented on Affymetrix GeneChips.

**

Stable RNAs were excluded from calculations.

††

As appropriate.

‡‡

Sixty-six genes were not represented on Affymetrix GeneChips.