Effect of EcoSSB on N4 vRNAP runoff transcription of the ssDNA
template 12-P2–52. (A) Where indicated, EcoSSB and
vRNAP were present at 1 μM and 10 nM, respectively. (B) A
100-μl complete transcription mixture containing 1 nM template but no
EcoSSB was divided into four aliquots (I, II, III, and IV) before
incubation at 37°C. I, no additions; II, 50 nM template was added after 20
min incubation; III, 1 μM EcoSSB was added before incubation; and
IV, 1 μM EcoSSB was added after 20 min of incubation. At the
indicated times, 5-μl aliquots were analyzed.