Table 2. TgPVR21 mouse neurovirlence test with type-3 polioviruses.
Paralyzed mice (in groups of 10)
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Dose (log10 TCID50)
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Virus strain | 1 | 2 | 3 | 4 | 5 | 6 | PD50 (log10 TCID50) |
Leon/37 | 6 | 10 | 10 | 10 | 10 | nd | <1.0 |
11264 | 5 | 10 | 10 | 10 | 10 | 10 | 1 |
Sabin 3 | nd | 1 | 1 | 6 | 10 | 10 | 3.2 |
TCID50, tissue culture 50% infective dose; PD50, 50% of the paralytic dose.