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. 2006 Dec;11(4):295–303. doi: 10.1379/1466-1268(2006)11[295:AOTCBA]2.0.CO;2

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Copyright © 2006, Cell Stress Society International

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Fig 1. — Domain structures of human Hap50/BAG-1L, Hap46/BAG-1M, and Hap33/BAG-1S. Potential nuclear localization signals (vertical hatching) between positions 68 and 79, as well as 219 and 234, in Hap50/BAG-1L. Basic DNA binding domain (horizontal hatching) between positions 72 and 79 in Hap50/BAG-1L (overlap with 1 of the potential nuclear localization signals in Hap50/BAG-1L is indicated by cross-hatching). The sequence is Met-Lys-Lys-Lys-Thr-Arg-Arg-Arg-Ser. Acidic hexarepeat domain between positions 81 and 140 in Hap50/BAG-1L; consensus sequence: Thr-Arg-Ser-Glu-Glu-X. Ubiquitin-like domain between positions 182 and 205 in Hap50/BAG-1L. Hsp70/Hsc70 binding domain = BAG domain between positions 272 and 319 in Hap50/BAG-1L (shown here as originally defined by Takayama et al 1999)