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. 2006 Dec;11(4):295–303. doi: 10.1379/1466-1268(2006)11[295:AOTCBA]2.0.CO;2

Fig 4.

Fig 4.

 Molecular model for the chaperoning of transcription factors by Hap46/BAG-1M. A simplified version of the transcriptional initiation complex is shown arbitrarily with 3 molecules of Hap46/BAG-1M bound to DNA; these are shown to establish various contacts via Hsp70 chaperones. Pol II, RNA polymerase II; TFII, basal transcription factor II; RE, response element on DNA; BP, specific response element binding protein, for example, a steroid hormone receptor complexed with its specific ligand (from Gehring 2004)