Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Dec 22;2(12):e216. doi: 10.1371/journal.pgen.0020216

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2006 Bandyopadhyay et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A–D) Forelimb of adult wild-type (A) and Bmp2^C/C; Prx1::cre mouse (B) and hindlimbs of newborn wild-type (C) mouse and newborn Bmp2^C/C; Bmp4^C/C; Prx1::cre (D) mouse. The black arrow in (B) shows soft tissue syndactyly in Bmp2^C/C; Prx1::cre mouse.

(E and F) Wild-type and Bmp2^C/C; Bmp4^C/C; Prx1::cre, respectively, showing acridine orange–stained hindlimbs of E15.5 mouse embryos. Acridine orange stain is in yellow.

(G and H) Enlarged views of selected regions from (E) and (F), respectively. Black arrow in (G) and (H) show acridine orange–stained apoptotic cells in the interdigital mesenchyme, and asterisk in (H) shows the remnant of the AER.

(I and J) Fgf8 mRNA expression in the hindlimbs of E13.5 wild-type (I) and Bmp2^C/C; Bmp4^C/C; Prx1::cre (J) embryos. The thick black arrows in (J) show Fgf8 mRNA expression.