IL-1β and IL-6 production after SES-induced peritoneal inflammation in wild-type and IFN-γ–/– mice. (a) Wild-type or IFN-γ–/– mice were intraperitoneally administered with PBS or SES. At specific time intervals, mice were sacrificed, and intraperitoneal IL-1β levels were quantified using ELISA (*P < 0.05 versus PBS). (b) Wild-type or IFN-γ–/– mice were intraperitoneally administered with PBS, SES, IFN-γ (0.5 U per mouse), or a combination of SES and IFN-γ. Intraperitoneal IL-6 levels were quantified at defined time intervals (*P < 0.05 versus IFN-γ–/– plus SES alone). The lower panels show wild-type and IFN-γ–/– mice treated with PBS alone. Values represent the mean ± SEM (n = 6 mice per condition).