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. 1988 Aug;43(2):119–125.

A genetical model for vitiligo.

P P Majumder 1, S K Das 1, C C Li 1
PMCID: PMC1715367  PMID: 3400640

Abstract

A genetical model is found to provide a good fit to family data on vitiligo. The model postulates that recessive alleles at a set of four unlinked diallelic loci are involved in the causation of the disorder. Under this multiple recessive homozygosis model, for normal X affected families ascertained through the affected parent, the expected segregation probability is .063; the estimated value is 0.53, which is not significantly different from the expected value. For normal X normal families ascertained through an affected offspring, the expected segregation probability is .037; the estimated value is .04.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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