Table 3.
Signature Gene Sets for pN Metastasis and ECS Based on the Intersection of Three Different Expression Indices.
| Signature Gene Set for pN+/- | Signature Gene Set for ECS+/- | ||||||
| Probe ID | Gene Title | Gene Symbol | Intersect* | Probe ID | Gene Title | Gene Symbol | Intersect* |
| Genes upregulated in pN+ cases | Genes upregulated in ECS+ cases | ||||||
| 226368_at | Carbohydrate sulfotransferase 11 | CHST11 | 2 | 205100_at | Glutamine-fructose-6-phosphate transaminase 2 | GFPT2 | 2 |
| 214782_at | Cortactin | CTTN | 3 | 204318_s_at | G-2 and S-phase expressed 1 | GTSE1 | 3 |
| 204318_s_at | G-2 and S-phase expressed 1 | GTSE1 | 2 | 236524_at | β-Amyloid binding protein precursor | BBP | 2 |
| 214375_at | PTPRF-interacting protein, binding protein 1 | PPFIBP1 | 2 | 205290_s_at | Bone morphogenetic protein 2 | BMP2 | 2 |
| 218414_s_at | Nude, A. nidulans, homolog of, 1 | NDE1 | 2 | 226368_at | Carbohydrate sulfotransferase 11 | CHST11 | 2 |
| 219557_s_at | Nuclear receptor interacting protein 3 | NRIP3 | 2 | 214782_at | Cortactin | CTTN | 2 |
| 223940_x_at | Metastasis-associated lung adenocarcinoma transcript 1 | MALAT1 | 2 | 229579_s_at | Dispatched homolog 2 | DISP2 | 3 |
| 210235_s_at | Protein tyrosine phosphatase, receptor type, of polypeptide, interacting protein, α1 | PPFIA1 | 3 | 232120_at | Epidermal growth factor receptor | EGFR | 2 |
| 242509_at | MGC17624 protein | MGC17624 | 2 | 203936_s_at | Matrix metalloproteinase 9 | MMP9 | 2 |
| 1553185_at | RAS and EF hand domain containing | RASEF | 3 | 219557_s_at | Nuclear receptor interacting protein 3 | NRIP3 | 2 |
| 236947_at | Semaphorin 3C | SEMA3C | 3 | 1559400_s_at | Pregnancy-associated plasma protein A, pappalysin 1 | PAPPA | 3 |
| 215715_at | Solute carrier family 6, member 2 | SLC6A2 | 2 | 213577_at | Squalene epoxidase | SQLE | 2 |
| 243834_at | Trinucleotide repeat containing 6A | TNRC6A | 3 | 243834_at | Trinucleotide repeat containing 6A | TNRC6A | 3 |
| 216450_x_at | Tumor rejection antigen 1 | TRA1 | 2 | 242554_at | Two pore segment channel 2 | TPCN2 | 2 |
| 229574_at | Transformer-2 α | TRA2A | 2 | ||||
| 244871_s_at | Ubiquitin-specific protease 32 | USP32 | 2 | ||||
| 226176_s_at | Ubiquitin-specific protease 42 | USP42 | 2 | ||||
| Genes downregulated in pN+ cases | Genes downregulated in ECS+ cases | ||||||
| 208848_at | Alcohol dehydrogenase 5, chi polypeptide | ADH5 | 2 | 209864_at | Frequently rearranged in advanced T-cell lymphomas 2 | FRAT2 | 2 |
| 224655_at | Adenylate kinase 3 | AK3 | 2 | 1555419_a_at | N-acylsphingosine amidohydrolase 1 | ASAH1 | 2 |
| 210980_s_at | N-acylsphingosine amidohydrolase 1 | ASAH1 | 2 | 213902_at | N-acylsphingosine amidohydrolase 1 | ASAH1 | 3 |
| 209366_x_at | Cytochrome b-5 | CYB5 | 2 | 212096_s_at | Mitochondrial tumor suppressor 1 | MTUS1 | 2 |
| 225864_at | Family with sequence similarity 84B | FAM84B | 2 | 226622_at | Mucin 20 | MUC20 | 2 |
| 211569_s_at | l-3-hydroxyacyl-coenzyme A dehydrogenase, short chain | HADHSC | 2 | 202174_s_at | Pericentriolar material 1 | PCM1 | 2 |
| 1555037_a_at | Isocitrate dehydrogenase 1 | IDH1 | 3 | 210145_at | Phospholipase A2, group IVA | PLA2G4A | 2 |
| 227297_at | Integrin, α9 | ITGA9 | 2 | 215772_x_at | Succinate-coenzyme A ligase, GDP-forming, β subunit | SUCLG2 | 2 |
| 212956_at | KIAA0882 protein | KIAA0882 | 2 | 200883_at | Ubiquinol-cytochrome c reductase core protein II | UQCRC2 | 2 |
| 222603_at | KIAA1815 | KIAA1815 | 2 | ||||
| 204249_s_at | LIM domain only 2 | LMO2 | 2 | ||||
| 202174_s_at | Pericentriolar material 1 | PCM1 | 2 | ||||
| 212096_s_at | Mitochondrial tumor suppressor 1 | MTUS1 | 3 | ||||
| 223130_s_at | Myosin light chain interacting protein | MYLIP | 2 | ||||
| 209120_at | Nuclear receptor subfamily 2, group F, member 2 | NR2F2 | 2 | ||||
| 223315_at | Netrin 4 | NTN4 | 2 | ||||
*
Number of times presented in the dChip-, MAS 5.0-, and RMA-based significant gene lists.