Table 3.

In Situ Hybridization hTR in Several Melanocytic Conditions.

	Number of Specimens	In Situ hTR*
Benign nevi
CMN/JMN	9	-
Primary melanoma
Clark II†	NA	NA
Clark III‡	1	+
Clark IV§	10	+
Metastases of melanoma
LNM	2	+
SCM	4	+

^*≥ 10 grains over the nucleus = +; < 10 grains over the nucleus = -.

^†Penetrates papillary dermis.

^‡Fills papillary dermis.

^§Penetrates reticular dermis.

CMN/JMN, compound melanocytic nevi/junctional melanocytic nevi; NA, not available; LNM, lymph node metastases; SCM, subcutaneous metastases of melanoma.