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. 2006 Dec 26;3(12):e525. doi: 10.1371/journal.pmed.0030525

Figure 5. An 80% Plaque Reduction Neutralization Titers (PRNT80) for VRP-S and VRP-S+N Hyperimmune Serum.

Figure 5

(A) Mice vaccinated young: icSARS-CoV (left) and icGDO3-S (right) PRNT80 for VRP-S immune serum (experiment 2) collected at 5 wk post-boost (n = 5) and 53 wk post-boost (n = 8).

(B) Mice vaccinated old: icSARS (left) and icGDO3-S (right) PRNT80 values for VRP-S and VRP-S+N immune serum (experiment 4) at 12 and 29 wk post-boost (n = 6 for icSARS; n = 5 for icGDO3-S). The PRNT80 values for individual animals are show as black circles, and the mean value is shown as a solid bar. The limits of detection (1:1,600 upper and 1:100 lower) are represented by horizontal dotted lines.