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Mice were exposed to a single dose of 250 (a), 500 (b), or 2,000 (c) J/m2 UVB. At various times after irradiation, WT (closed bars), Xpa−/− (crosshatched bars), Xpc−/− (hatched bars), and Csb−/− (open bars) mice were killed. Sections (5 μm) were made from skin biopsies and the number of caspase 3-positive epidermal cells per arbitrary unit (a.u.) was counted. Data are means ± SEM (n ≥ 3) or variation (n = 2).
