Table 1.
Differential expression profiles of cell cycle and DNA synthesis/repair genes between wild-type and PARP−/− primary fibroblasts
| Accession no.* | Fold Δ† | Gene name |
|---|---|---|
| Cell cycle control | ||
| z26580 | −2.1 | Cyclin A |
| AA426917 | −2.7 | Cyclin B1 |
| X66032 | −2.1 | Cyclin B2 |
| AA000468 | −2 | p55CDC |
| AA123463 | −2 | SET protein |
| W90992 | 2.9 | Cyclin D2 |
| W08016 | 2.2 | Cyclin D1 |
| z37110 | 3.5 | Cyclin G |
| M37761 | 2 | Calcyclin |
| X58876 | 3.3 | MDM2 |
| U09507 | 2 | p21 |
| DNA-RNA synthesis/repair | ||
| d13544 | −3.1 | DNA primase small subunit |
| X53068 | −2 | Proliferating cell nuclear antigen (PCNA) |
| X14805 | −3.2 | DNA methyltransferase 1 |
| u08110 | −2 | RNA1 homolog (Fug1) |
| X52875 | 5.5 | Homeobox protein Prx2 |
| M31885 | 3 | Helix-loop-helix DNA binding protein regulator (Id) |
| AA107455 | 1.8 | Elongation factor 2 |
| W40670 | 4.9 | Adenylate kinase isoenzyme 1 |
| Chromosomal processing and assembly | ||
| Z46757 | −6.8 | HMG-2 |
| M37736 | −2.4 | Histone H2A.1 |
| z31235 | −3.2 | pr22 microtubule protein |
| Protein Processing | ||
| aa545125 | −2.5 | Ubiquitin conjugating enzyme E2 |
*
GenBank accession no.
†
Fold increase or decrease in expression in PARP−/− cells relative to that in wild-type cells.