Figure 3.

Phylogenetic tree for mammalian Vh germ-line sequences. The phylogenetic analyses were performed for 85 Vh exon 2 sequences, each 261 bp, as described above (see Fig. 2 and Materials and Methods). The tree shown is the consensus of the 54 trees (length = 396,410 steps) obtained with the weighted maximum parsimony analysis. Bootstrap proportions are indicated on the branches in black. The colors of the branches indicate the group to which the human Vh coding sequences belong, as described in Fig. 2. At the branch extremity, a circle indicates that the RSS is known and is colored as shown in the key to indicate RSS type. Nonhuman sequences are designated with the genus of the animal followed by the GenBank accession number.