Table 1.
Increase of NK, NK-T, CD8, and γδ T cells in two strains (B1 and K2) of the IL-15 transgenic mouse
| NK, % in lymphocytes
|
NK-T, % in
lymphocytes
|
CD4, % in lymphocytes
|
CD8,
% in CD3 T cells
|
γδ dendritic epidermal T cells
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Wt | B1 | K2 | Wt | B1 | K2 | Wt | B1 | K2 | Wt | B1 | K2 | Wt | K2 | |
| Bone marrow | 0.8 | NT | 7.6 | 0.7 | NT | 4.7 | NT | NT | NT | NT | NT | NT | NT | NT |
| Liver | 16.1 | 15.5 | 33.3 | 11.3 | 20.9 | 30.7 | NT | NT | NT | 31.7 | NT | 80.1 | NT | NT |
| Spleen | 3.4 | 4.1 | 8.0 | 2.7 | 1.5 | 4.6 | 13.2 | 12.6 | 11.2 | 33.8 | 41.2 | 74.2 | NT | NT |
| Thymus | 0 | NT | 0.2 | 0.5 | NT | 1.6 | 11.2 | NT | 6.8 | 30.8 | NT | 28.4 | NT | NT |
| Skin | NT | NT | NT | NT | NT | NT | NT | NT | NT | NT | NT | NT | 1,080 ± 173 (mm2) | 10,122 ± 661 (mm2) |
NT, Not tested.