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. 1997 Oct;81(10):852–856. doi: 10.1136/bjo.81.10.852

Intraocular pressure and central visual field of normal tension glaucoma

M Araie 1, M Kitazawa 1, N Koseki 1
PMCID: PMC1722024  PMID: 9486025

Abstract

AIM—To study whether damage in the central 30° field of normal tension glaucoma (NTG) is relatively heterogeneous or homogeneous with respect to intraocular pressure (IOP) related damage.
METHODS—Using the results of Humphrey perimeter examinations, the central 30° field was divided into four subfields; superior and inferior hemifields excluding the caecocentral field (30-2 program) and superior and inferior 10° hemifields (10-2 program). In 103 NTG cases, the intraindividual bilateral difference in the mean of total deviations (mean TD) in the four subfields was analysed by multiple linear regression to correct the effects of factors other than IOP. Explanatory variables were the intraindividual bilateral difference in the mean of clinic IOP (IOPmean), that in the ratio of area of peripapillary atrophy corresponding to each subfield to disc area, and that in myopic refraction.
RESULTS—The intraindividual bilateral difference in the mean TD was significantly and negatively correlated with that in IOPmean in three of the above four subfields (p<0.005) and correlation tended to be negative (p=0.07) in the superior 10° hemifield.
CONCLUSIONS—Diffuse IOP related damage was suggested in the central 30° field of NTG; greater extent of the damage in the above four subfields was correlated with higher mean IOP. The present findings may have clinical implications.



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Figure 1  .

Figure 1  

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Distribution of test points presently used. Open rhombi are test points for central 10° superior hemifield, open squares those for central 10° inferior hemifield, open circles those for superior hemifield excluding caecocentral field, and open triangles those for inferior hemifield excluding caecocentral field. Closed squares and circles are those excluded from the present analysis.

Selected References

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