Physiological effect of NO synthase inhibition and exercise on forearm
blood flow. Forearm blood flow measurements, expressed as
ml/min/100 g tissue, were performed at baseline, during L-NMMA
infusion, and during L-NMMA infusion with hand-grip exercise. Basal
forearm blood flow was significantly reduced from 2.79 ± 0.34
ml/min per 100 ml of tissue to 2.04 ± 0.22 ml/min per 100 ml
of tissue (P = 0.001) during L-NMMA infusion (data
shown represent the average of measurements made during the morning and
the repeated afternoon study in 10 individuals). Exercise, during
L-NMMA infusion, significantly increased blood flow to 14.50 ±
1.71 ml/min per 100 ml of tissue (P < 0.001).
Data are expressed as the mean ± SEM.