Figure 2.

Measurements of ONL thickness in rats killed at different ages. □ denote normal wild-type (WT), nontransgenic animals. P23H-3 transgenic (Tg) rats were either uninjected (■) or injected subretinally with rAAV vectors carrying either Hp11 (●) or Hh13 (⧫) ribozymes. All injections were done at P15. The symbols represent mean ± SD, and error bars were omitted if they fell within the symbol. The number of animals in each group is shown in Table 1. The data points at P60, P75, and P90 are taken from our earlier study (25).