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Gene transfer in conjunctiva. Using our mouse model of conjunctival scarring,33 we have shown that there is transduction of fibroblasts and mononuclear cells in the subconjunctival space with an AV vector expressing a lacZ reporter gene (AV.CMV.LacZnuc). Positive expression is indicated by galactosidase activity seen as blue (nuclear fast red counterstain, 5 µm section, ×80 magnification).
