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Co-localisation of TGF-β2 and GFAP by immunofluorescence in the lamina cribrosa of a glaucomatous donor (age 92 years old). In (A) immunoreactivity for TGF-β2 is localised to cells inside the cribriform plates (CP) and in the nerve bundles (NB). These cells are also GFAP positive, confirming their identity as astrocytes (B). (C) Illustrates the co-localisation of TGF-β2 and GFAP. Arrows point to some of the cells that show double staining. ×400.
